13 CBD Facts You Need to Know

Sharpen your understanding of CBD with this overview of facts and myths you need to know. Perfect for the novice to the expert, and anyone else that’s interested in learning about CBD as its popularity rapidly evolves— this CBD fact guide will walk you through the most foundational aspects of the cannabinoid so you can finally have clarity.

CBD Comes From Cannabis

Found within Cannabis Sativa L. (marijuana and hemp plants), are over a hundred cannabinoids, terpenes, flavonoids, nutrients, and more. One of those intriguing cannabinoids is Cannabidiol, also known as CBD. This major cannabinoid is heavily dispersed throughout the aerial parts of the plant, or above the soil line; such as the flowers, leaves, and stems.

CBD is Non-Intoxicating

CBD is a non-psychotropic compound that does not alter your perception or behavior, contrary to some CBD myths. The fact is that with a standard dosage of CBD, you will not experience a state of euphoria or get “high.” It’s been easy to villainize cannabis plants for its intoxicating effects— which are owed to a different cannabinoid, THC. However, it’s important to understand that not all cannabinoids are the same, just like not all cannabis plants are the same. Additionally, therapeutic benefits are not always lost on compounds that do have psychotropic properties or mobilize non-traditional perspectives.

The Endocannabinoid System is How it Works

The genius of biological design revealed itself once again with the discovery of the Endocannabinoid System (ECS) in the late 1960s. The ECS is a network of chemical signals and cellular receptors that are dispersed throughout the brain and body. It exists in all animals and has an important role of regulating a wide range of the body’s natural functions, including sleep, memory, mood, reflexes, recovery, and so much more. Our body naturally produces endocannabinoids, cannabinoid receptors, and enzymes. Yet, research has shown that taking CBD supplement products can also have a positive impact on the ECS regulation processes that guide us towards a state of homeostasis. More CBD Facts: How CBD Works in The Body

Animals Respond to CBD

As mentioned, all animals, including vertebrates (mammals, reptiles, birds, and fish) and invertebrates (sea urchins, mussels, leeches, and more) are equipped with an endocannabinoid system [1]. Research shows that animals successfully respond to cannabinoid supplementation in a similar way that humans do. With consistent usage, CBD pet products can help animals by supporting their general immune health, while also reducing anxiety, inflammation, pain, and preventing seizures from reoccurring. Explore: Neurogan CBD for Pets Read More CBD Facts: Neurogan’s Guide- Best CBD for Dogs

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Fact: CBD is Federally Legal

Hemp-derived CBD is legal in the United States under federal law. The 2018 Farm Bill provides stability, clarity, and support for those navigating the CBD industry when there previously was a lack of established guidelines to follow. Parameters include that hemp and products containing its natural derivatives cannot contain more than 0.3% THC in its dry weight.

Not All CBD Products Are Made Equal

CBD-rich hemp flower buds have been used for smoking, steeping into tea, and extracting oil to be made into tinctures, gummies, softgel capsules, body lotions, and more. Your CBD experience can vary significantly based on the quality of hemp used, manufacturing performance, and general bioavailability of these different product types. Bioavailability refers to how much of the active ingredient makes it into your bloodstream and exerts its effects. For instance, although CBD edibles are convenient, their absorption rate is particularly low with an average of 19%. Contrarily, smoking CBD is the most effective and fastest way to feel its benefits and has an average absorption rate upwards of 56% [2]. Read More CBD Facts: CBD Bioavailability—How to Harness the Power of CBD

CBD Dosage Will Vary

Many individuals wonder how much CBD is right for them. But the fact is that CBD dosage varies person to person, and the myth is that all CBD works the same on all people. There are multiple factors that influence what is the proper dosage for someone— including body weight, sensitivity, medical conditions, wellness goals, and product type. CBD products are typically available with a dosage range of 5mg-120mg CBD per serving. If you’re brand new to cannabinoids or trying a different brand, we would advise starting with a small dose of 10mg and observing your body’s response before taking more. Check Out More CBD Facts: CBD Gummies Dosage Guide— How Many CBD Gummies Should I Eat?

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Always Review 3rd Party Lab Test

While pure CBD is recognized as a safe and effective cannabinoid, the CBD fact is that you should always review a 3rd party Certificate of Analysis (COA), also known as a lab test, for the raw hemp and finished cannabis derived products. Some farmers use harmful contaminants during the growing process— such as pesticides, heavy metals, and solvents. (Which is why it is equally important to choose organic hemp products as it is to examine lab tests). Additionally, production quality can range significantly amongst CBD companies and there is the risk of unhealthy ingredients being added to the CBD product.

3rd Party Lab Tests Reveal:

Factual, Scientific Research On CBD Has Increased

The United States Federal Government is lifting limitations on cannabis research after over 50 years of resistance. With the signing of the 2018 Farm Bill there has been a momentous uptick in production of cannabis for medical and scientific purposes.

This change is accelerating our understanding of the effects of cannabis and its therapeutic health benefits for treating medical conditions such as epilepsy, multiple sclerosis, chronic pain, sleep disorders, and more.

At this time however, the majority of clinical research on cannabis and cannabinoids is considered to still be in its preliminary stages. Continued studies are necessary to have a long-standing understanding of its effectiveness and tolerability [3].

CBD is Safe, Effective, and Non-Addictive

The World Health Organization has made the following statements as a result of the comprehensive scientific evidence that developed around CBD facts:

• CBD is generally well tolerated with a good safety profile
• CBD exhibits no effects indicative of any abuse or dependence potential—a strong CBD fact and disapproval of this myth
• To date, there is no evidence of recreational use of CBD or any public health-related problems associated with the use of pure CBD

The WHO recognizes that there is currently no evidence that CBD use is related to major health concerns and is believed to have many potential benefits for therapeutic use.

Limited FDA Approval of CBD

The U.S. Food and Drug Administration (FDA) has approved only one cannabis product and three cannabis related products that are concluded as safe and effective for its intended use.

A prescription drug called Epidiolex, contains a purified form of cannabidiol CBD, and is used in the treatment of a rare epilepsy and seizure disease in patients 1 years of age and older. Other than Epidiolex, the CBD fact is that there is no other hemp-derived CBD product that is FDA-approved.

With the stacking evidence favoring the medical use of CBD, as well as the advancement of sophisticated structures for manufacturing and laboratory testing for safety, the FDA’s pace for approving and regulating CBD can feel negligent for the millions of users and prospective users of CBD.

CBD is Used For Therapeutic Benefits

“CBD has been shown to be beneficial in experimental models of several neurological disorders, including those of seizure and epilepsy.” – Anna K. Abram (FDA Deputy Commissioner)

The scientific evidence of CBD’s therapeutic benefits is developing within multiple arenas of health. Extensive research shows the promising effectiveness of CBD dietary supplements for general wellness benefits and also for more complex health conditions such as epilepsy, sleep disorders, chronic pain, anxiety, depression, and addiction recovery.

CBD has been FDA-approved as a drug for the treatment of epilepsy and is recognized for its long-term safety profile for the medical condition.

Epilepsy is a neurological disorder that is characterized by recurrent seizures. These convulsions consist of loss of muscle control, involuntary muscle contractions, and localized tremors or spasms.

Fortunately, CBD can help to prevent seizures in humans and animals by reducing neuron excitability in the Transient Receptor Potential Vanilloid (TRPP), and G Protein-Coupled Receptor 55 (GPR55) [4].

Sleep

CBD is used as a natural remedy for resolving the common symptoms of insomnia and other sleep disorders.

While pharmaceutical sleep medications induce sleep by acting as a depressant to the brain and central nervous system, CBD works with the endocannabinoid system to promote homeostasis throughout the body and influence our circadian rhythm, or our internal process that regulates the sleep/wake cycle.

Insomnia is a sleep disorder that makes it difficult to achieve quality sleep and is associated with an overactive stress response in the night. CBD helps to mitigate insomnia by engaging regulation processes that lower stress hormones and promotes relaxation that helps you fall asleep and stay asleep.

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Anxiety and Depression

The first clinical studies examining CBD’s potential therapeutic benefits for anxiety and depression were conducted in 1974 and 1982. Because of CBD’s safety profile and neurological benefits, the topic of CBD’s impact on anxiety and depression has remained a leading focus for scientific research.

While clinical evidence exists in the preliminary stages of CBD research, results have shown CBD significantly reduces subjective anxiety both in a rapid and consistent manner in patients diagnosed with anxiety disorder.

Additionally, CBD has been observed to reduce depressive and psychotic-like symptoms and improve attentional switching, verbal learning, and memory. Experts believe that CBD’s potential to treat depression is related to its positive effect on serotonin receptors in the brain.

Pain

The Centers for Disease Control and Prevention (CDC) estimates that chronic pain affects nearly 50 million Americans, or approximately 20.4% of adults in the United States. The search for a non-addictive solution has led to the thorough examination of CBD for the treatment of chronic pain in extensive clinical studies.

CBD’s inflammatory response capabilities help to mitigate discomfort and chronic pain in the body. CBD has been shown to resolve cellular damage, lessen oxidative stress, lower pain signals, and encourage the normal recovery process.

While studies are currently preliminary and continuing research is necessary for a more comprehensive understanding of how CBD affects pain, CBD has shown success in treatments for neuropathic pain, multiple sclerosis, arthritis and more [5].

Addiction Recovery

CBD may be a safer alternative to dangerous pharmaceutical drugs and a remedy to the addictions it causes.

By inducing a deep sense of relaxation and mitigating anxiety, CBD may help individuals work through the physical, mental, and emotional dependencies of addiction that make quitting so difficult.

According to recent studies, CBD oil could be a promising smoking cessation treatment for its anxiolytic properties and has been shown to modulate drug cue salience, with minimal side effects [6].

CBD Has Adverse Effects

While CBD has a reliable safety profile, at high doses or when mixed with other medications it may show unwanted adverse effects including drowsiness, headaches, nausea, and dry mouth.

These side effects are temporary and expected to subside within 4–6 hours. However, if side effects do not resolve on their own, then please seek medical supervision from your healthcare provider.

Side Effects:

Drug Tests Do Not Screen for CBD

Contrary to popular CBD myths, the fact of the matter is that drug tests do not screen for CBD because it is a non-intoxicating compound that doesn’t alter your behavior or performance.

Contrarily, drug tests will be searching for tetrahydrocannabinol (THC), and some CBD products do contain traces of this psychotropic compound. If you’re not careful, you could have a positive drug test after having a CBD product.

If you are seeking the benefits of taking CBD but want to be certain you do not fail a drug test, then stick with a THC-free broad spectrum extract.

Takeaways

The scientific community and public have shown a growing interest in the Cannabis Sativa plant and CBD due to their good safety profile and neurological benefits, and it doesn’t seem like that fascination is going anywhere soon.

With its recent legal status, evolving research disapproving of CBD myths and solidifying facts, promising evidence of therapeutic benefits, and exploding market, the need to discern fact from fiction will allow us to have an honest and effective relationship with the cannabinoid.

We hope that exploring these CBD facts you need to know will advance your general knowledge of the cannabinoid and help you to exercise care should you decide to use a CBD dietary supplement.

FAQ

What is CBD?

CBD, or cannabidiol, is a naturally occurring compound found in marijuana and hemp plants, along with over a hundred other compounds like cannabinoids, terpenes, flavonoids, and nutrients. CBD oil interacts with the endocannabinoid system, a complex network of receptors, transmitters, and enzymes in the body that helps regulate various processes such as mood, memory, emotions, and sleep.

How long does CBD stay in your system?

The duration that CBD stays in your system is difficult to determine precisely, as several factors influence this, including the method of CBD consumption, the frequency of usage, and the potency of the product. Moreover, the effects of CBD and its stay in your system vary from person to person due to their unique response to CBD.

Is CBD addictive?

According to the World Health Organization, based on the extensive scientific evidence available on CBD, there is no indication that CBD use is associated with significant health risks, and it is not considered to be addictive. Instead, CBD is believed to have various potential therapeutic benefits.

Can CBD get you high?

CBD is a non-intoxicating compound, which means it does not cause any alterations in your behavior or perception. Therefore, contrary to some misconceptions about CBD, it does not get you “high.” In fact, with a regular dose of CBD, you will not experience euphoria or any other psychoactive effects.

References:

1. Silver RJ. The Endocannabinoid System of Animals. Animals (Basel). 2019 Sep 16;9(9):686. doi: 10.3390/ani9090686. PMID: 31527410; PMCID: PMC6770351.
2. Huestis MA. Human cannabinoid pharmacokinetics. Chem Biodivers. 2007 Aug;4(8):1770-804. doi: 10.1002/cbdv.200790152. PMID: 17712819; PMCID: PMC2689518.
3. https://www.npr.org/sections/health-shots/2021/05/30/1000867189/after-50-years-u-s-opens-the-door-to-more-cannabis-crops-for-scientists
4. Silvestro S, Mammana S, Cavalli E, Bramanti P, Mazzon E. Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials. Molecules. 2019 Apr 12;24(8):1459. doi: 10.3390/molecules24081459. PMID: 31013866; PMCID: PMC6514832.
5. Booz GW. Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. Free Radic Biol Med. 2011 Sep 1;51(5):1054-61. doi: 10.1016/j.freeradbiomed.2011.01.007. Epub 2011 Jan 14. PMID: 21238581; PMCID: PMC3085542.
6. Prud’homme M, Cata R, Jutras-Aswad D. Cannabidiol as an Intervention for Addictive Behaviors: A Systematic Review of the Evidence. Subst Abuse. 2015 May 21;9:33-8. doi: 10.4137/SART.S25081. PMID: 26056464; PMCID: PMC4444130.

BY

Belinda Hoang

BS in Business Belinda draws inspiration from the intersection of nature and humanity, finding depth in the experiences they offer. Her journey as an educational leader, starting from meditation guide, has led her to advocate for the therapeutic benefits of hemp and plant apothecary. As Neuroga.

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